{"id":5903,"date":"2015-09-05T11:36:57","date_gmt":"2015-09-05T11:36:57","guid":{"rendered":"https:\/\/isbpath.wickedcode.com\/?page_id=5903"},"modified":"2018-01-07T19:23:26","modified_gmt":"2018-01-07T19:23:26","slug":"case-study-preview","status":"publish","type":"page","link":"https:\/\/isbpath.wickedcode.com\/index.php\/case-study-preview\/","title":{"rendered":"Case Study Preview"},"content":{"rendered":"[fusion_builder_container hundred_percent=\"yes\" overflow=\"visible\"][fusion_builder_row][fusion_builder_column type=\"2_5\" last=\"no\" spacing=\"yes\" center_content=\"no\" hide_on_mobile=\"no\" background_color=\"\" background_image=\"\" background_repeat=\"no-repeat\" background_position=\"left top\" border_position=\"all\" border_size=\"\" border_color=\"\" border_style=\"solid\" padding=\"\" margin_top=\"\" margin_bottom=\"\" animation_type=\"0\" animation_direction=\"down\" animation_speed=\"0.1\" class=\"\" id=\"\"][fusion_images picture_size=\"auto\" hover_type=\"zoomin\" autoplay=\"yes\" columns=\"1\" column_spacing=\"1\" scroll_items=\"\" show_nav=\"yes\" mouse_scroll=\"no\" border=\"no\" lightbox=\"yes\" class=\"\" id=\"\"][fusion_image link=\"\" linktarget=\"_self\" image=\"https:\/\/isbpath.wickedcode.com\/wp-content\/uploads\/2015\/08\/11-e1441144520994.jpg\" alt=\"\"\/][fusion_image link=\"\" linktarget=\"_self\" image=\"https:\/\/isbpath.wickedcode.com\/wp-content\/uploads\/2015\/08\/21.jpg\" alt=\"\"\/][fusion_image link=\"\" linktarget=\"_self\" image=\"https:\/\/isbpath.wickedcode.com\/wp-content\/uploads\/2015\/08\/31.jpg\" alt=\"\"\/][fusion_image link=\"\" linktarget=\"_self\" image=\"https:\/\/isbpath.wickedcode.com\/wp-content\/uploads\/2015\/08\/41.jpg\" alt=\"\"\/][fusion_image link=\"\" linktarget=\"_self\" image=\"https:\/\/isbpath.wickedcode.com\/wp-content\/uploads\/2015\/08\/51.jpg\" alt=\"\"\/][\/fusion_images][fusion_text]\r\n
CLICK PHOTO TO ENLARGE<\/span><\/h5>\r\n[\/fusion_text][fusion_separator style_type=\"none\" top_margin=\"3\" bottom_margin=\"3\" sep_color=\"\" border_size=\"\" icon=\"\" icon_circle=\"\" icon_circle_color=\"\" width=\"\" alignment=\"center\" class=\"\" id=\"\"\/][\/fusion_builder_column][fusion_builder_column type=\"3_5\" last=\"yes\" spacing=\"yes\" center_content=\"no\" hide_on_mobile=\"no\" background_color=\"\" background_image=\"\" background_repeat=\"no-repeat\" background_position=\"left top\" border_position=\"all\" border_size=\"0px\" border_color=\"\" border_style=\"\" padding=\"\" margin_top=\"\" margin_bottom=\"\" animation_type=\"\" animation_direction=\"\" animation_speed=\"0.1\" class=\"\" id=\"\"][fusion_text]\r\n

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Case #:<\/h4>\r\n[\/fusion_text][fusion_text]6[\/fusion_text][fusion_separator style_type=\"single solid\" top_margin=\"1\" bottom_margin=\"1\" sep_color=\"#cccccc\" border_size=\"1px\" icon=\"\" icon_circle=\"\" icon_circle_color=\"\" width=\"\" alignment=\"center\" class=\"\" id=\"\"\/][fusion_text]\r\n

Presented by:<\/h4>\r\n[\/fusion_text][fusion_text]Dr Benjamin Yongcheng Tan\r\nDepartment of Pathology, Singapore General Hospital[\/fusion_text][fusion_separator style_type=\"single solid\" top_margin=\"1\" bottom_margin=\"1\" sep_color=\"#cccccc\" border_size=\"1px\" icon=\"\" icon_circle=\"\" icon_circle_color=\"\" width=\"\" alignment=\"center\" class=\"\" id=\"\"\/][fusion_text]\r\n

Clinical History:<\/h4>\r\n[\/fusion_text][fusion_text]A 61-year-old Asian female with hemodialysis-dependent end-stage renal failure and a significant medical history of hypertension, diabetes mellitus, deep vein thrombosis, and pulmonary embolism presented with progressive enlargement of her left arm and breast. Magnetic resonance imaging revealed left axillary vein thrombosis extending to the left subclavian vein, without significant axillary lymphadenopathy. She had a previous episode of left upper limb cellulitis, which resolved after inpatient management. Owing to failure of conservative treatment, which included a period of compression garment therapy, the patient elected for a mastectomy.[\/fusion_text][fusion_separator style_type=\"single solid\" top_margin=\"1\" bottom_margin=\"1\" sep_color=\"#cccccc\" border_size=\"1px\" icon=\"\" icon_circle=\"\" icon_circle_color=\"\" width=\"\" alignment=\"center\" class=\"\" id=\"\"\/][fusion_text]\r\n

Pathology:<\/h4>\r\n[\/fusion_text][fusion_text]Macroscopic findings:<\/em>\u00a0The left simple mastectomy specimen measured 31cm x 30cm x 9cm and weighed 4.1kg. The overlying skin showed generalised brawny discolouration. Sectioning the breast revealed an edematous appearance with copious clear fluid oozing from the cut surfaces. \u00a0A well-circumscribed nodule measuring 1.1cm in diameter was identified within the breast substance.\r\n\r\nMicroscopic findings:<\/em>\u00a0Extensive, marked stromal edema and areas of fibrosis were present. The grossly-identified nodule comprised a circumscribed proliferation of variably-sized vessels, containing luminal and stromal lymphocytes, lined by bland, mitotically-inactive endothelial cells highlighted by D2-40 immunohistochemical stain. No evidence of in-situ or invasive malignancy was present.[\/fusion_text][fusion_separator style_type=\"single solid\" top_margin=\"1\" bottom_margin=\"1\" sep_color=\"#cccccc\" border_size=\"1px\" icon=\"\" icon_circle=\"\" icon_circle_color=\"\" width=\"\" alignment=\"center\" class=\"\" id=\"\"\/][fusion_text]\r\n

Diagnosis:<\/h4>\r\n[\/fusion_text][fusion_text]---[\/fusion_text][fusion_separator style_type=\"single solid\" top_margin=\"1\" bottom_margin=\"25\" sep_color=\"#cccccc\" border_size=\"1px\" icon=\"\" icon_circle=\"\" icon_circle_color=\"\" width=\"\" alignment=\"center\" class=\"\" id=\"\"\/][fusion_accordion divider_line=\"no\" class=\"\" id=\"\"][fusion_toggle title=\"Discussion:\" open=\"no\"]---[\/fusion_toggle][\/fusion_accordion][fusion_separator style_type=\"single solid\" top_margin=\"1\" bottom_margin=\"25\" sep_color=\"#cccccc\" border_size=\"1px\" icon=\"\" icon_circle=\"\" icon_circle_color=\"\" width=\"\" alignment=\"center\" class=\"\" id=\"\"\/][\/fusion_builder_column][fusion_builder_column type=\"1_1\" background_position=\"left top\" background_color=\"\" border_size=\"\" border_color=\"\" border_style=\"solid\" spacing=\"yes\" background_image=\"\" background_repeat=\"no-repeat\" padding=\"\" margin_top=\"0px\" margin_bottom=\"0px\" class=\"\" id=\"\" animation_type=\"\" animation_speed=\"0.3\" animation_direction=\"left\" hide_on_mobile=\"no\" center_content=\"no\" min_height=\"none\"][fusion_separator style_type=\"none\" top_margin=\"35\" bottom_margin=\"35\" sep_color=\"\" border_size=\"\" icon=\"\" icon_circle=\"\" icon_circle_color=\"\" width=\"\" alignment=\"center\" class=\"\" id=\"\"\/][\/fusion_builder_column][\/fusion_builder_row][\/fusion_builder_container]","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-5903","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/isbpath.wickedcode.com\/index.php\/wp-json\/wp\/v2\/pages\/5903","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/isbpath.wickedcode.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/isbpath.wickedcode.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/isbpath.wickedcode.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/isbpath.wickedcode.com\/index.php\/wp-json\/wp\/v2\/comments?post=5903"}],"version-history":[{"count":3,"href":"https:\/\/isbpath.wickedcode.com\/index.php\/wp-json\/wp\/v2\/pages\/5903\/revisions"}],"predecessor-version":[{"id":7065,"href":"https:\/\/isbpath.wickedcode.com\/index.php\/wp-json\/wp\/v2\/pages\/5903\/revisions\/7065"}],"wp:attachment":[{"href":"https:\/\/isbpath.wickedcode.com\/index.php\/wp-json\/wp\/v2\/media?parent=5903"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}